2026/11/14 09:00-10:30 Room 301
- Emerging Risk Factors in Stroke
- Time
- Topic
- Speaker
- Moderator
- 09:30-10:00
- Beyond BMI: The Weight of Evidence in Stroke Seconary Prevention
- SPEAKER:
Yu-Chang Chen
陳昱彰
Taiwan (台灣)
- MODERATOR:
Cheng-Yang Hsieh
謝鎮陽
Taiwan (台灣)
Giia-Sheun Peng
彭家勛
Taiwan (台灣)
- Yu-Chang Chen
- MD
-
Chief of Community Medicine, Pingtung E-DA Hospital, Taiwan
Attending Physician, Department of Family and Community Medicine, E-DA Hospital, Taiwan
Physician, Weight Management Center, E-DA Hospital, Taiwan
Lecture Abstract：
Obesity is an important contributor to vascular risk, but its relationship with stroke cannot be fully understood through body mass index alone. This lecture examines how obesity influences stroke risk and whether treating obesity improves cerebrovascular outcomes.
The discussion will review general and central adiposity, metabolic risk factors, and differences across stroke subtypes. The obesity paradox will be examined in relation to study populations, outcome selection, reverse causation, and selection bias. Particular emphasis will be placed on distinguishing the risk of a first stroke from prognosis and recurrence after stroke, and on separating observational associations from causal effects of treatment.
Selected evidence on lifestyle interventions, obesity pharmacotherapy, and metabolic surgery will be critically appraised, including glucagon-like peptide-1 receptor agonists and dual incretin therapies. Changes in weight and cardiometabolic risk factors will be considered separately from effects on stroke and composite cardiovascular outcomes. Findings will be interpreted according to study populations and their relevance to primary and secondary stroke prevention.
Integrating evidence available at the time of presentation, the lecture will outline a practical approach to patient selection and comprehensive risk reduction. Clinical decisions will consider adiposity distribution, diabetes and other comorbidities, nutritional status, muscle function, and treatment tolerability, alongside established preventive measures.
Obesity is an important contributor to vascular risk, but its relationship with stroke cannot be fully understood through body mass index alone. This lecture examines how obesity influences stroke risk and whether treating obesity improves cerebrovascular outcomes.
The discussion will review general and central adiposity, metabolic risk factors, and differences across stroke subtypes. The obesity paradox will be examined in relation to study populations, outcome selection, reverse causation, and selection bias. Particular emphasis will be placed on distinguishing the risk of a first stroke from prognosis and recurrence after stroke, and on separating observational associations from causal effects of treatment.
Selected evidence on lifestyle interventions, obesity pharmacotherapy, and metabolic surgery will be critically appraised, including glucagon-like peptide-1 receptor agonists and dual incretin therapies. Changes in weight and cardiometabolic risk factors will be considered separately from effects on stroke and composite cardiovascular outcomes. Findings will be interpreted according to study populations and their relevance to primary and secondary stroke prevention.
Integrating evidence available at the time of presentation, the lecture will outline a practical approach to patient selection and comprehensive risk reduction. Clinical decisions will consider adiposity distribution, diabetes and other comorbidities, nutritional status, muscle function, and treatment tolerability, alongside established preventive measures.
